Anticorps Recombinant de lapin anti-PSMA/GCPII

PSMA/GCPII Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242026E6

N° de cat : 98279-1-PBS

Synonymes

FOLH1, PSMA, 242026E6, Cell growth-inhibiting gene 27 protein, EC:3.4.17.21

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Galerie de données de validation

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  FC experiment of LNCaP using 98279-1-RR (same clone as 98279-1-PBS)

  1x10^6 LNCaP cells (left) or HeLa (right) were surface stained with 0.25 ug Anti-Human FOLH1 Rabbit RecAb (98279-1-RR, Clone: 242026E6) (red),or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue)and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98279-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98279-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98279-1-RR against Human PSMA/GCPII were performed. The affinity constant is 49.6 nM.

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Informations sur le produit

98279-1-PBS cible PSMA/GCPII dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: folate hydrolase (prostate-specific membrane antigen) 1
• Masse moléculaire calculée: 84KD
• Numéro d’acquisition GenBank: NM_004476.3
• Symbole du gène: PSMA
• Identification du gène (NCBI): 2346
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

PSMA (Prostate-specific membrane antigen) is also named as FOLH1, FOLH, NAALAD1, PSM and belongs to the peptidase M28 family. PSMA is a 100-120 kDa integral transmembrane glycoprotein, considered to be a highly specific marker of the prostate gland, and has successfully been used as a marker of circulating prostatic epithelial cells(PMID:10074909; 15680901). It is involved in conversion of the major neurotransmitter (NAAG) to NAA and free glutamate. It has 8 isoforms produced by alternative splicing.

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