Anticorps Monoclonal anti-PSMB7

PSMB7 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3D7B8

N° de cat : 68641-1-PBS

Synonymes

Z, Proteasome subunit beta type-7, EC:3.4.25.1, 3D7B8

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Galerie de données de validation

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  WB analysis using 68641-1-Ig (same clone as 68641-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68641-1-Ig (PSMB7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 68641-1-Ig (same clone as 68641-1-PBS)

  Immunohistochemical analysis of paraffin-embedded skin cancer slide using 68641-1-Ig (PSMB7 antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68641-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68641-1-PBS cible PSMB7 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PSMB7 Protéine recombinante Ag6544
• Nom complet: proteasome (prosome, macropain) subunit, beta type, 7
• Masse moléculaire calculée: 29.9 kDa
• Poids moléculaire observé: 28-30 kDa
• Numéro d’acquisition GenBank: BC000509
• Symbole du gène: PSMB7
• Identification du gène (NCBI): 5695
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. PSMB7 protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. Component of the 20S core proteasome complex are involved in the proteolytic degradation of most intracellular proteins. PSMB7 displays a trypsin-like activity.(PMID:15244466, PMID:27176742, PMID: 8610016)

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