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Anticorps Recombinant de lapin anti-PSMD14/POH1

PSMD14/POH1 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242160H6

N° de cat : 84767-4-PBS

Synonymes

PSMD14, POH1, PAD1, EC:3.4.19.-, 26S proteasome-associated PAD1 homolog 1

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of A375 cells using PSMD14/POH1 Recombinant antibody (84767-4-RR)

    IF Staining of A375 using 84767-4-RR (same clone as 84767-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A375 cells using PSMD14 antibody (84767-4-RR, Clone: 242160H6 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84767-4-PBS in a different storage buffer formulation.

Informations sur le produit

84767-4-PBS cible PSMD14/POH1 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène PSMD14/POH1 Protéine recombinante Ag2694
Nom complet proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Masse moléculaire calculée 35 kDa
Numéro d’acquisition GenBankBC009524
Symbole du gène PSMD14
Identification du gène (NCBI) 10213
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The PSMD14 (POH1, also known as Rpn11/MPR1/S13/CepP1) protein is a metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. PSMD14 is highly expressed in the heart and skeletal muscle. In carcinoma cell lines. down-regulation of PSMD14 by siRNA transfection considerably impacted cell viability, causing cell arrest in the G0-G1 phase, ultimately leading to senescence.

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