Anticorps Monoclonal anti-PSMD2

PSMD2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G7G5

N° de cat : 67770-1-PBS

Synonymes

TRAP2, S2, Rpn1, P97, 26S proteasome non-ATPase regulatory subunit 2

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Galerie de données de validation

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  WB analysis using 67770-1-Ig (same clone as 67770-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67770-1-Ig (PSMD2 antibody) at dilution of 1:50000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67770-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67770-1-PBS cible PSMD2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PSMD2 Protéine recombinante Ag6543
• Nom complet: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
• Masse moléculaire calculée: 100 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC002368
• Symbole du gène: PSMD2
• Identification du gène (NCBI): 5708
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.

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