Anticorps Polyclonal de lapin anti-PTGER3

PTGER3 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14357-1-PBS

Synonymes

EP3, EP3 I, EP3 II, EP3 III, EP3 IV

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Galerie de données de validation

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  IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14357-1-AP (same clone as 14357-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14357-1-AP (PTGER3 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14357-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14357-1-PBS cible PTGER3 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PTGER3 Protéine recombinante Ag5711
• Nom complet: prostaglandin E receptor 3 (subtype EP3)
• Masse moléculaire calculée: 43 kDa
• Numéro d’acquisition GenBank: BC024229
• Symbole du gène: PTGER3
• Identification du gène (NCBI): 5733
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PTGER3 (Prostaglandin E Receptor 3), also known as EP3, is a G protein-coupled receptor (GPCR). Activates pathways involved in proliferation, migration, and apoptosis, often via cross-talk with PI3K-AKT and MAPK cascades (PMID: 38566528). High PTGER3 levels drive tumorigenesis, angiogenesis, and cisplatin resistance via the Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis (PMID: 30655206).

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