Anticorps Monoclonal anti-PTPIP51

PTPIP51 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G11E2

N° de cat : 68582-1-PBS

Synonymes

FAM82A2, 1G11E2, FAM82C, hRMD 3, hRMD-3

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Galerie de données de validation

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  WB analysis using 68582-1-Ig (same clone as 68582-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68582-1-Ig (PTPIP51 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 68582-1-Ig (same clone as 68582-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using PTPIP51 antibody (68582-1-Ig, Clone: 1G11E2 ) at dilution of 1:476 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68582-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68582-1-PBS cible PTPIP51 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PTPIP51 Protéine recombinante Ag15135
• Nom complet: family with sequence similarity 82, member A2
• Masse moléculaire calculée: 470 aa, 52 kDa
• Poids moléculaire observé: 52-60 kDa
• Numéro d’acquisition GenBank: BC008970
• Symbole du gène: PTPIP51
• Identification du gène (NCBI): 55177
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protein tyrosine phosphatase-interacting protein 51 (PTPIP51),also known as RMDN3, is a mitochondrial membrane-anchored protein that interacts with ER membrane-bound VAPB. The VAPB-PTPIP51 interaction impacts on intracellular Ca2+ handling (PMID: 22131369, 28345618). PTPIP51 participates in multiple cellular processes, and dysfunction of PTPIP51 is implicated in diseases such as cancer and neurodegenerative disorders (PMID: 28345618).The known initiation sites in the Ptpip51 gene would lead to molecular protein masses of 52, 38 and 30 kDa (PMID: 18854601,19844996).

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