Anticorps Monoclonal anti-PTPN2

PTPN2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A1D1

N° de cat : 67388-1-PBS

Synonymes

2A1D1, EC:3.1.3.48, PTN2, PTPN 2, PTPT

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Galerie de données de validation

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  WB analysis using 67388-1-Ig (same clone as 67388-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  WB analysis using 67388-1-Ig (same clone as 67388-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  WB analysis of 4T1 using 67388-1-Ig (same clone as 67388-1-PBS)

  4T1 cells were subjected to SDS PAGE followed by western blot with 67388-1-Ig (PTPN2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 67388-1-Ig (same clone as 67388-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67388-1-Ig (PTPN2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 67388-1-Ig (same clone as 67388-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67388-1-Ig (PTPN2 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67388-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67388-1-PBS cible PTPN2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PTPN2 Protéine recombinante Ag29749
• Nom complet: protein tyrosine phosphatase, non-receptor type 2
• Masse moléculaire calculée: 49 kDa
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: BC016727
• Symbole du gène: PTPN2
• Identification du gène (NCBI): 5771
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PTPN2(Tyrosine-protein phosphatase non-receptor type 2) is also named as PTPT and belongs to the protein-tyrosine phosphatase family. It may modulate beta-cell apoptosis and/or local release of inflammatory mediators in the course of a viral infection by acting, at least in part, at the pancreatic beta-cell level(PMID: 19825843). This protein has some isoforms produced by alternative splicing with the molecular mass of 40-50 kDa.

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