Anticorps Polyclonal de lapin anti-PTPRM/RPTPmu

PTPRM/RPTPmu Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30763-1-PBS

Synonymes

PTPRM, EC:3.1.3.48, hR PTPu, Protein-tyrosine phosphatase mu, PTPRL1

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Galerie de données de validation

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  WB analysis using 30763-1-AP (same clone as 30763-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30763-1-AP (PTPRM antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30763-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 30763-1-AP (same clone as 30763-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30763-1-AP (PTPRM antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30763-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30763-1-PBS cible PTPRM/RPTPmu dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PTPRM/RPTPmu Protéine recombinante Ag33475
• Nom complet: protein tyrosine phosphatase, receptor type, M
• Masse moléculaire calculée: 164KD
• Poids moléculaire observé: 80 kDa, 100 kDa, 200 kDa
• Numéro d’acquisition GenBank: NM_002845
• Symbole du gène: PTPRM
• Identification du gène (NCBI): 5797
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PTPRM, also known as protein tyrosine phosphatase receptor type M or RPTPmu, is a protein with a molecular weight of approximately 155 kDa. It is a receptor-type tyrosine phosphatase involved in cell-cell adhesion, migration, and signaling. It exists in two forms, either a full-length 200 kDa form or as two noncovalently associated fragments of 100 kDa each.Additional unidentified serine proteases cleave PTPμ in GBM cells to yield smaller extracellular fragments with MWs of 78 and 55 kDa (PMID: 25223585).

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