Anticorps Polyclonal de lapin anti-PTPRR

PTPRR Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 17937-1-PBS

Synonymes

Ch-1PTPase, EC PTP, EC:3.1.3.48, ECPTP, NC-PTPCOM1

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Galerie de données de validation

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  WB analysis using 17937-1-AP (same clone as 17937-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 17937-1-AP (same clone as 17937-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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  WB analysis of COLO 320 using 17937-1-AP (same clone as 17937-1-PBS)

  COLO 320 cells were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 17937-1-AP (same clone as 17937-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 17937-1-AP (PTPRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17937-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17937-1-PBS cible PTPRR dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PTPRR Protéine recombinante Ag12145
• Nom complet: protein tyrosine phosphatase, receptor type, R
• Masse moléculaire calculée: 657 aa, 74 kDa
• Poids moléculaire observé: 32 kDa, 47 kDa, 65 kDa
• Numéro d’acquisition GenBank: BC110900
• Symbole du gène: PTPRR
• Identification du gène (NCBI): 5801
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PTPRR(protein tyrosine phosphatase, receptor type, R) is also named as PCPTP1, PTP-SL, PTPBR7 and belongs to the protein-tyrosine phosphatase family. It sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. It has four isoforms that they have molecular weights of 72, 60, 42 and 37 kDa, respectively, and differ in the length of their N-terminal part which result in distinct subcellular localizations. All PTPRR isoforms are found to be short-lived proteins, with half-lives of around 3-5 hours, and are constitutively phosphorylated on one or two of the previously identified protein kinase A and MAP kinase target sites.

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