Anticorps Polyclonal de lapin anti-PTPRZ1

PTPRZ1 Polyclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(8)

N° de cat : 55125-1-AP

Synonymes

HPTPZ, HPTPzeta, HTPZP2, phosphacan, PTP ZETA, PTP18, PTPRZ, PTPRZ1, PTPRZ2, PTPZ, R PTP zeta, R PTP zeta 2, RPTPB, RPTPbeta

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Galerie de données de validation

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  WB analysis of HepG2 using 55125-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 55125-1-AP (PTPRZ1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of HeLa using 55125-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 55125-1-AP (PTPRZ1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  IHC staining of rat cerebellum using 55125-1-AP

  Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue slide using 55125-1-AP (PTPRZ1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of rat cerebellum using 55125-1-AP

  Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue slide using 55125-1-AP (PTPRZ1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en WB: cellules HepG2, cellules HeLa
• Résultats positifs en IHC: tissu de cervelet de rat, ; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000
• Immunohistochimie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IHC: See 4 publications below
• IF: See 3 publications below

Informations sur le produit

55125-1-AP cible PTPRZ1 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: protein tyrosine phosphatase, receptor-type, Z polypeptide 1
• Masse moléculaire calculée: 255 kDa
• Poids moléculaire observé: 163-175 kDa
• Numéro d’acquisition GenBank: NM_002851
• Symbole du gène: PTPRZ1
• Identification du gène (NCBI): 5803
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PTPRZ1, also named as HTPZP2, PTPRZ, PTPRZ2 and PTPZ, belongs to the protein-tyrosine phosphatase family and Receptor class 5 subfamily. It may be involved in the regulation of specific developmental processes in the CNS. PTPRZ1 has some isoforms with MW 254 kDa, 163 kDa and 90 kDa.

Publications

Species	Application	Title
mouse	WB	J Clin Invest; Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.; Authors - Zhixiong Liu
human	WB,IHC	J Oncol; Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.; Authors - Liwei Ma
human	IHC	Heliyon; IL-34 and its receptors as predictors of brain metastasis and prognosis in lung adenocarcinoma: Unveiling insights through bioinformatic and immunohistochemical investigations; Authors - Jianxiong Geng
human	IHC	Rapid Commun Mass Spectrom; Data-independent acquisition combined with liquid chromatography mass spectrometry technique to detect prognostic protein markers in type I gastric neuroendocrine neoplasm; Authors - Meng Zhang
mouse	IF	iScience; Single-nucleus RNA sequencing-based construction of a hippocampal neuron atlas in mice with epileptic cognitive impairment; Authors - Jia-Qi Ma
human	IHC	Oncogene; PTPRZ1 dephosphorylates and stabilizes RNF26 to reduce the efficacy of TKIs and PD-1 blockade in ccRCC; Authors - Yongkang Ma

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