Anticorps Recombinant de lapin anti-PYGB

PYGB Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251450C3

N° de cat : 86737-3-PBS

Synonymes

EC:2.4.1.1, GPBB, phosphorylase, glycogen; brain

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Galerie de données de validation

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  WB analysis using 86737-3-RR (same clone as 86737-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86737-3-RR (PYGB antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86737-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86737-3-RR

  Biolayer interferometry (BLl) kinetic assays of 86737-3-RR against Human PYGB were performed. The affinity constant is below 1 pM.

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Informations sur le produit

86737-3-PBS cible PYGB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PYGB Protéine recombinante Ag2732
• Nom complet: phosphorylase, glycogen; brain
• Masse moléculaire calculée: 843 aa, 97 kDa
• Poids moléculaire observé: 97 kDa
• Numéro d’acquisition GenBank: BC017045
• Symbole du gène: PYGB
• Identification du gène (NCBI): 5834
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The three main subtypes of GP found in human tissues-brain-type glycogen phosphorylase (PYGB), liver-type glycogen phosphorylase (PYGL), and muscle-type glycogen phosphorylase (PYGM)-differ in function, structure, and tissue distribution. PYGB (Brain‑type glycogen phosphorylase) is a glycogen phosphorylase and is primarily localized in adult brain tissues and embryo liver tissues, whose function is to provide energy to organisms (PMID: 30106110). PYGB has been observed to be overexpressed in many types of cancer and tumor cell lines and is expected to be a novel target for the diagnosis and treatment of various cancers (PMID: 38334681).

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