Anticorps Polyclonal de lapin anti-Pannexin 3

Pannexin 3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31736-1-PBS

Synonymes

PANX3, PX3

---

Galerie de données de validation

• 

  WB analysis using 31736-1-AP (same clone as 31736-1-PBS)

  U2OS cells were subjected to SDS PAGE followed by western blot with 31736-1-AP (Pannexin 3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31736-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

31736-1-PBS cible Pannexin 3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Pannexin 3 Protéine recombinante Ag34451
• Nom complet: pannexin 3
• Masse moléculaire calculée: 392 aa, 45 kDa
• Poids moléculaire observé: 43 kDa
• Numéro d’acquisition GenBank: NM_052959
• Symbole du gène: PANX3
• Identification du gène (NCBI): 116337
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Pannexin 3 (PANX3) is a member of the pannexin family of single membrane channel-forming glycoproteins. PANX3 is expressed in osteoblasts, chondrocytes, and skin and plays a major role in calcium homeostasis suggesting an independent functional niche. PANX3 regulates both chondrocyte and osteoblast differentiation via the activation of intracellular Ca2+ signaling pathways through multiple channel activities: hemichannels, endoplasmic reticulum (ER) Ca2+ channels, and gap junctions. PANX3 has 392 amino acids with a molecular weight of ~ 43 kDa and is N-linked glycosylated at asparagine residue 71 in the first extracellular loop (PMID: 27837015, PMID: 34250568, PMID: 38580658).

{{ptg:RelatedPrimaryAntibodies}}