Anticorps Polyclonal de lapin anti-Periostin

• Phare
• Validé par KD/KO

Periostin Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 19899-1-PBS

Synonymes

OSF 2, OSF2, OSF-2, Osteoblast specific factor 2, Osteoblast-specific factor 2

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Galerie de données de validation

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  IHC staining of human skin cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 19899-1-AP (Periostin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 19899-1-AP (Periostin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 19899-1-AP (same clone as 19899-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

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Informations sur le produit

19899-1-PBS cible Periostin dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Periostin Protéine recombinante Ag13791
• Nom complet: periostin, osteoblast specific factor
• Masse moléculaire calculée: 93 kDa
• Numéro d’acquisition GenBank: BC106710
• Symbole du gène: Periostin
• Identification du gène (NCBI): 10631
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Periostin (POSTN, PN), originally named as osteoblast-specific factor 2 (OSF-2), is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues, and has a role in bone, tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types, including lung, ovary, breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour, and it is required to allow cancer stem cell maintenance. The isoforms of periostin are between 83 and 93 kDa in mass and differ in their C-terminal sequences, characterized by individual presence or absence of cassette exons 17-21 (UniProtKB/Swiss-Prot,PMID: 21997759).

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