Anticorps Polyclonal de lapin anti-Phospho-PKC Delta (Thr507)

Phospho-PKC Delta (Thr507) Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29564-1-PBS

Synonymes

PKC delta, PRKCD, PKCD, nPKC-delta, MAY1

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Galerie de données de validation

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  WB analysis using 29564-1-AP (same clone as 29564-1-PBS)

  Non-treated and PMA treated THP-1 cells were subjected to SDS PAGE followed by western blot with 29564-1-AP (Phospho-PKC Delta (Thr507) antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with PKC Delta antibody (19132-1-AP) subsequently. This data was developed using the same antibody clone with 29564-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29564-1-PBS cible Phospho-PKC Delta (Thr507) dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: protein kinase C, delta
• Masse moléculaire calculée: 78 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC043350
• Symbole du gène: PKC Delta
• Identification du gène (NCBI): 5580
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PKC Delta(PRKCD) is a member of the PKC family, a phospholipid-dependent family of serine/threonine kinases, and is present in human neutrophils. Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine. Three specific sites; Thr-507 (activation loop of the kinase domain), Ser-645 (turn motif) and Ser-664 (hydrophobic region), need to be phosphorylated for its full activation. This antibody is equivalent to Thr505 in mice.

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