Anticorps Recombinant de lapin anti-Phospho-TAU (Ser202/Thr205)

Phospho-TAU (Ser202/Thr205) Recombinant Antibody for WB, IF-P, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF-P, ELISA

Conjugaison

Non conjugué

Publications(3)

CloneNo.

4A6

N° de cat : 82568-1-RR

Synonymes

p TAU, p TAU (Ser202/Thr205), p TAU Ser202/Thr205, Phospho TAU, Phospho TAU (Ser202/Thr205)



Applications testées

Résultats positifs en WBtissu cérébral de souris
Résultats positifs en IF-Ptissu cérébral de souris

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Immunofluorescence (IF)-PIF-P : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

WBSee 3 publications below

Informations sur le produit

82568-1-RR cible Phospho-TAU (Ser202/Thr205) dans les applications de WB, IF-P, ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Réactivité citéesouris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Peptide
Nom complet microtubule-associated protein tau
Masse moléculaire calculée 37-46, 79-81 kDa
Poids moléculaire observé45-55 kDa
Numéro d’acquisition GenBankBC000558
Symbole du gène TAU
Identification du gène (NCBI) 4137
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Tau (tubulin-associated unit) is a microtubule-associated protein (also known as MAPT), expressed mainly in neurons of the central nervous system. Its primary function is to modulate microtubule dynamics for maintaining axonal cytoskeleton. The Tau protein has six isoforms produced from a single gene through alternative RNA splicing. Isoforms differ in number of inserts at the N-terminal half and the number of repeats at the C-terminal half (3 repeat-3R; 4 repeat-4R). Tau is hyperphosphorylated during aging and in age-related neurodegenerative diseases such as Alzheimer's disease (AD) and fronto-temporal dementia. Hyperphosphorylation of Tau leads to the formation of neurofibrillary tangles (NFT) in the neurons and glia cells, which is one of the hallmarks of AD.

Protocole

Product Specific Protocols
WB protocol for Phospho-TAU (Ser202/Thr205) antibody 82568-1-RRDownload protocol
IF protocol for Phospho-TAU (Ser202/Thr205) antibody 82568-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Foods

Comparative Analysis of Egg Yolk Phospholipid Unsaturation and Its Impact on Neural Health in Alzheimer Disease Mice

Authors - Yuhang Sun
mouseWB

Open Life Sci

Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease

Authors - Shiguo Lin
mouseWB

Exp Clin Endocrinol Diabetes

Beneficial effects of Echinacoside on cognitive impairment and diabetes in type 2 diabetic db/db mice

Authors - Fanglin Qin

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Camille (Verified Customer) (02-17-2025)

We used the antibody 82568-1-RR for an IHC on human samples and it worked nicely at a dilution of 1/1000

  • Applications: Immunohistochemistry
  • Primary Antibody Dilution: 1/1000
FH

Marion (Verified Customer) (11-21-2024)

This antibody was tested to reveal Tau phosporylation in a murine AD model. We are satisfied with the results.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1/400
  • Cell Tissue Type: Mouse Brain
Phospho-TAU (Ser202/Thr205) Antibody Immunofluorescence validation (1/400 dilution) in Mouse Brain (Cat no:82568-1-RR)
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