Anticorps Monoclonal anti-Plasminogen

Plasminogen Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, IF-P, ELISA

Conjugaison

Non conjugué

CloneNo.

1F6A11

N° de cat : 66399-1-PBS

Synonymes

PLG, 1F6A11, Angiostatin, EC:3.4.21.7, Plasmin heavy chain A, short form

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Galerie de données de validation

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  WB analysis of human plasma using 66399-1-Ig (same clone as 66399-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66399-1-Ig (PLG Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66399-1-Ig (PLG Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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  IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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  IF Staining of human liver cancer using 66399-1-Ig (same clone as 66399-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 66399-1-Ig (same clone as 66399-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using Plasminogen antibody (66399-1-Ig, Clone: 1F6A11 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 66399-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66399-1-PBS cible Plasminogen dans les applications de WB, IHC, IF/ICC, IF-P, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Plasminogen Protéine recombinante Ag9938
• Nom complet: plasminogen
• Masse moléculaire calculée: 810 aa, 91 kDa
• Poids moléculaire observé: 105 kDa
• Numéro d’acquisition GenBank: BC060513
• Symbole du gène: Plasminogen
• Identification du gène (NCBI): 5340
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.

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