Anticorps Polyclonal de lapin anti-Polycystin 1

Polycystin 1 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22263-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human liver using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieved with Sodium Citrate buffer (pH 6.0). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22263-1-PBS cible Polycystin 1 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: polycystic kidney disease 1 (autosomal dominant)
• Masse moléculaire calculée: 463 kDa
• Numéro d’acquisition GenBank: NM_000296
• Symbole du gène: Polycystin 1/PKD1
• Identification du gène (NCBI): 5310
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Polycystin 1 (PC1) is also named as PKD1, and Autosomal dominant polycystic kidney disease 1 protein, and belongs to the polycystin family. PKD1 and PKD2 are formed component of a heteromeric calcium-permeable ion channel. PKD1 is considered an orphan, atypical G protein coupled receptor complexed with TRPP2 (Polycystin 2 or PKD2), a Ca2+-permeable ion channel (PMID:27214281). PKD1 is involved in renal tubulogenesis (PMID:12482949).

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