Anticorps Recombinant de lapin anti-Prion protein PrP/CD230

Prion protein PrP/CD230 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

243104D11

N° de cat : 98414-4-PBS

Synonymes

Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP

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Galerie de données de validation

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  FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

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Informations sur le produit

98414-4-PBS cible Prion protein PrP/CD230 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Prion protein PrP/CD230 Protéine recombinante Eg3359
• Nom complet: prion protein
• Numéro d’acquisition GenBank: BC012844
• Symbole du gène: PrP
• Identification du gène (NCBI): 5621
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

The major prion protein (PrP), also known as CD230, is encoded by the prion protein-encoding gene (PRNP). PrP is widely expressed in a variety of tissues and is abundant in the nervous system and participates in neuronal growth and survival. PrP expression is strongly associated with immune infiltrating cells, immunosuppressive cell infiltration and immune checkpoint molecules. PrP is an immune-related prognostic marker that holds promise for predicting outcomes related to colorectal cancer immunotherapy.

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