Anticorps Recombinant de lapin anti-Coagulation factor II

Coagulation factor II Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243089F11

N° de cat : 86124-1-PBS

Synonymes

F2, Prothrombin, Activation peptide fragment 1, Activation peptide fragment 2, EC:3.4.21.5

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Galerie de données de validation

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  WB analysis of human plasma using 86124-1-RR (same clone as 86124-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 86124-1-RR (Prothrombin/F2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86124-1-PBS in a different storage buffer formulation.

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  Cytometric bead array sample test of MP02277-1

  The mean Coagulation Factor II/F2 concentration was determined to be 986.4 ug/mL in human serum.

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  Cytometric bead array standard curve of MP02277-1

  Cytometric bead array standard curve of MP02277-1, Coagulation Factor II/F2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 86124-2-PBS. Detection antibody: 86124-1-PBS. Standard: Eg1337. Range: 0.781-100 ng/mL.

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  Affinity and Kinetic Characterization of 86124-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86124-1-RR against Human Coagulation factor II were performed. The affinity constant is 54.6 nM.

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Informations sur le produit

86124-1-PBS cible Coagulation factor II dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Coagulation factor II Protéine recombinante Eg1337
• Nom complet: coagulation factor II (prothrombin)
• Masse moléculaire calculée: 70kDa
• Poids moléculaire observé: 72 kDa
• Numéro d’acquisition GenBank: NM_000506.5
• Symbole du gène: F2
• Identification du gène (NCBI): 2147
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Coagulation Factor II (F2), also known as prothrombin, is one of the components of this chain of plasma proteins involved in blood coagulation. Prothrombin is the precursor of thrombin, which is essential in the processes of hemostasis and thrombosis.

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