Anticorps Polyclonal de lapin anti-Prothymosin Alpha

Prothymosin Alpha Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10480-1-PBS

Synonymes

Prothymosin alpha, N-terminally processed, prothymosin, alpha, PTMA, Thymosin alpha-1

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Galerie de données de validation

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  IHC staining of human thyroid cancer using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 10480-1-AP (Prothymosin Alpha antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of rat colon using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat colon tissue slide using 10480-1-AP (Prothymosin Alpha antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10480-1-AP (same clone as 10480-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10480-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10480-1-PBS cible Prothymosin Alpha dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Prothymosin Alpha Protéine recombinante Ag0732
• Nom complet: prothymosin, alpha
• Masse moléculaire calculée: 12 kDa
• Numéro d’acquisition GenBank: BC003510
• Symbole du gène: Prothymosin Alpha/PTMA
• Identification du gène (NCBI): 5757
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

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