Anticorps Polyclonal de lapin anti-QKI

• Phare
• Validé par KD/KO

QKI Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13169-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13169-1-AP (same clone as 13169-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13169-1-AP (QKI antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 13169-1-AP (same clone as 13169-1-PBS)

  IP result of anti-QKI (IP:13169-1-AP, 4ug; Detection:13169-1-AP 1:400) with K-562 cells lysate 3600ug. This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 13169-1-AP (same clone as 13169-1-PBS)

  Immunohistochemical analysis of paraffin-embedded stomach cancer slide using 13169-1-AP (QKI antibody) at dilution of 1:300 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13169-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13169-1-PBS cible QKI dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: QKI Protéine recombinante Ag3822
• Nom complet: quaking homolog, KH domain RNA binding (mouse)
• Masse moléculaire calculée: 341 aa, 38 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC019917
• Symbole du gène: QKI
• Identification du gène (NCBI): 9444
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

QKI (Quaking) is RNA-binding protein that plays a central role in myelinization (PMID: 16641098). It regulates pre-mRNA splicing, mRNA export and protein translation (PMID: 16641098). It acts upstream of or within several processes, including long-chain fatty acid biosynthetic process, positive regulation of macromolecule metabolic process and vasculogenesis. QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism. It is expressed in the frontal cortex of brain (PMID: 16342280).

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