Anticorps Recombinant de lapin anti-QSOX1/Quiescin Q6

QSOX1/Quiescin Q6 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240946B11

N° de cat : 83952-3-PBS

Synonymes

QSOX1, QSCN6, Q6, hQSOX, EC:1.8.3.2

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Galerie de données de validation

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  WB analysis using 83952-3-RR (same clone as 83952-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83952-3-RR (QSOX1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83952-3-PBS in a different storage buffer formulation.

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Informations sur le produit

83952-3-PBS cible QSOX1/Quiescin Q6 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: QSOX1/Quiescin Q6 Protéine recombinante Ag3396
• Nom complet: quiescin Q6 sulfhydryl oxidase 1
• Masse moléculaire calculée: 747 aa, 83 kDa
• Poids moléculaire observé: 66-83kDa
• Numéro d’acquisition GenBank: BC017692
• Symbole du gène: QSOX1
• Identification du gène (NCBI): 5768
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

QSOX1(Sulfhydryl oxidase 1) catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.It has two isoforms with the molecular weight of 67 kda and 83 kDa,respectively. It is detected a band of 95 Kda in HT1080 cell lines (PMID:17331072).Isoform 1 is expressed on golgi apparatus membrane and isoform 2 is secreted (PMID:10708601). The isoform1(QSOX1a) is the full length of QSOX1, approximately 78 kd; and the isoform2(QSOX1b) is the splicing form, approximately 62kd(PMID:14633699; 2496424). QSOX1 is highly expressed in tumor cell lines but is not expressed in adjacent normal cells (PMID:21989104).

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