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Anticorps Polyclonal de lapin anti-QTRT1

QTRT1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12349-1-PBS

Synonymes

EC:2.4.2.64, FP3235, Guanine insertion enzyme, Queuine tRNA-ribosyltransferase catalytic subunit 1, TGT

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of HeLa cells using QTRT1 Polyclonal antibody (12349-1-AP)

    WB analysis of HeLa using 12349-1-AP (same clone as 12349-1-PBS)

    WB result of QTRT1 antibody (12349-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-QTRT1 transfected HeLa cells. This data was developed using the same antibody clone with 12349-1-PBS in a different storage buffer formulation.

Informations sur le produit

12349-1-PBS cible QTRT1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène QTRT1 Protéine recombinante Ag3010
Nom complet queuine tRNA-ribosyltransferase 1
Masse moléculaire calculée 403 aa, 44 kDa
Poids moléculaire observé 44 kDa
Numéro d’acquisition GenBankBC015350
Symbole du gène QTRT1
Identification du gène (NCBI) 81890
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

QTRT1 (Queuine tRNA-ribosyltransferase catalytic subunit 1), also known as tRNA-guanine transglycosylase (TGT), is a key enzymeinvolved in the post-transcriptional modification of tRNAs. In humans, the QTRT1 and QTRT2 heterodimer complex exhibits transglycosylase activity, and replaces the guanine base of the first letter of the tRNA anticodon with q, thus forming Q on the tRNA (PMID: 30149595, 25884661). High QTRT1 expression is a biomarkerfor poor prognosis in LUAD patients, and QTRT1 mayfunction as a latent tumor biomarker in the prognosticprediction for LUAD (PMID: 33490170).

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