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Anticorps Polyclonal de lapin anti-RAB17

RAB17 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17501-1-PBS

Synonymes

Ras-related protein Rab-17, Ras related protein Rab 17

Galerie de données de validation

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  • Immunohistochemistry (IHC) staining of human pancreas tissue using RAB17 Polyclonal antibody (17501-1-AP)

    IHC staining of human pancreas using 17501-1-AP (same clone as 17501-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 17501-1-AP (RAB17 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human pancreas tissue using RAB17 Polyclonal antibody (17501-1-AP)

    IHC staining of human pancreas using 17501-1-AP (same clone as 17501-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 17501-1-AP (RAB17 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of WIF-B cells using RAB17 Polyclonal antibody (17501-1-AP)

    IF Staining of WIF-B cells using 17501-1-AP (same clone as 17501-1-PBS)

    IF result of RAB17 antibody (17501-1-AP) with WIF-B cells overexpressed myc-tagged RAB17 by A.C. Striz and Dr. P.L. Tuma. This data was developed using the same antibody clone with 17501-1-PBS in a different storage buffer formulation.

Informations sur le produit

17501-1-PBS cible RAB17 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène RAB17 Protéine recombinante Ag11688
Nom complet RAB17, member RAS oncogene family
Masse moléculaire calculée 212 aa, 23 kDa
Numéro d’acquisition GenBankBC050426
Symbole du gène RAB17
Identification du gène (NCBI) 64284
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RAB17 is a member of the RAS oncogene family and is classified as a small GTPase that plays a crucial role in intracellular membrane trafficking It is specifically expressed in epithelial cells and is involved in various cellular functions such as transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. This process is mainly observed in epithelial cells and is important for the transcellular transport of substances like immunoglobulins from the basolateral surface to the apical surface. RAB17 is also implicated in the regulation of melanosome transport and release from melanocytes, which is critical for pigmentation in skin cells . Additionally, it has been suggested to regulate dendrite and dendritic spine development, which are important for neuronal function. The protein is involved in membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis.

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