Anticorps Recombinant de lapin anti-RAB37

RAB37 Recombinant Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240838D6

N° de cat : 83740-4-PBS

Synonymes

Ras-related protein Rab-37, Ras related protein Rab 37, 240838D6

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Galerie de données de validation

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  WB analysis using 83740-4-RR (same clone as 83740-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83740-4-RR (RAB37 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83740-4-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 83740-4-RR (same clone as 83740-4-PBS)

  IP result of anti-RAB37 (IP:83740-4-RR, 4ug; Detection:83740-4-RR 1:2000) with mouse brain tissue lysate 1840 ug. This data was developed using the same antibody clone with 83740-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83740-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83740-4-RR against Human RAB37 were performed. The affinity constant is 1.25 nM.

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Informations sur le produit

83740-4-PBS cible RAB37 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RAB37 Protéine recombinante Ag3717
• Nom complet: RAB37, member RAS oncogene family
• Masse moléculaire calculée: 223 aa, 25 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: BC016615
• Symbole du gène: RAB37
• Identification du gène (NCBI): 326624
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RAB37, as a small GTPase, plays important roles in several cellular processes through intracellular membrane traffic. RAB37 can regulate insulin secretion in β-cells 7 and TNF-α secretion from activated macrophages. In allergic responses, RAB37 regulated mast cell degranulation. RAB37 has been identified to be a tumor suppressor and it regulated exocytosis of several proteins including TIMP metallopeptidase inhibitor 1 (TIMP1), secreted frizzled-related protein-1 (SFRP1) 12, thrombospondin-1 (TSP1), and soluble ST2.

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