Anticorps Monoclonal anti-RAB3GAP2

RAB3GAP2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A4A1

N° de cat : 66648-1-PBS

Synonymes

DKFZp434D245, FLJ14579, KIAA0839, p150, Rab3 GAP p150, Rab3 GAP regulatory subunit, RAB3 GAP150, RAB3GAP150, RAB3GAP2, RGAP iso

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Galerie de données de validation

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  WB analysis using 66648-1-Ig (same clone as 66648-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66648-1-Ig (RAB3GAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66648-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66648-1-PBS cible RAB3GAP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: RAB3GAP2 Protéine recombinante Ag20254
• Nom complet: RAB3 GTPase activating protein subunit 2 (non-catalytic)
• Masse moléculaire calculée: 1393 aa, 156 kDa
• Poids moléculaire observé: 150 kDa
• Numéro d’acquisition GenBank: BC146760
• Symbole du gène: RAB3GAP2
• Identification du gène (NCBI): 25782
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RAB3GAP2, also known as RAB3-GAP150, belongs to the Rab3-GAP regulatory subunit family. Rab3 GAP consists of two subunits: the catalytic subunit p130 and the noncatalytic subunit p150. Rab3 GAP is ubiquitously expressed and enriched in the synaptic soluble fraction of brain, consistent with it having a key role in neurodevelopment. RAB3-GAP150 forms the Rab3 GTPase-activating complex with RAB3-GAP130,where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. Defects in RAB3-GAP150 are the cause of Martsolf and Warburg Micro syndrome.

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