Anticorps Polyclonal de lapin anti-RABGGTA

• Phare
• Validé par KD/KO

RABGGTA Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14448-1-PBS

Synonymes

EC:2.5.1.60, Geranylgeranyl transferase type-2 subunit alpha, Rab geranyl-geranyltransferase subunit alpha, Rab GG transferase alpha, Rab GGTase alpha

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Galerie de données de validation

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  WB analysis of HEK-293 using 14448-1-AP (same clone as 14448-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 14448-1-AP (RABGGTA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 14448-1-AP (same clone as 14448-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 14448-1-AP (RABGGTA antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung using 14448-1-AP (same clone as 14448-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 14448-1-AP (RABGGTA antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung using 14448-1-AP (same clone as 14448-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 14448-1-AP (RABGGTA antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14448-1-AP (same clone as 14448-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 14448-1-AP (RABGGTA antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14448-1-AP (same clone as 14448-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 14448-1-AP (RABGGTA antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 14448-1-AP (same clone as 14448-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 14448-1-AP (RABGGTA antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14448-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14448-1-PBS cible RABGGTA dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RABGGTA Protéine recombinante Ag5923
• Nom complet: Rab geranylgeranyltransferase, alpha subunit
• Masse moléculaire calculée: 65 kDa
• Poids moléculaire observé: 60~65 kDa
• Numéro d’acquisition GenBank: BC003093
• Symbole du gène: RABGGTA
• Identification du gène (NCBI): 5875
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GGTase II (RAB geranylgeranyl transferase, RABGGTase) is a heterodimer composed of tightly bound α- and β-subunits, which belongs to the Ras superfamily of small monomeric GTPases. RABGGTase is extensively involved in intracellular membrane trafficking of membrane-bound organelles and vesicles and specifically catalyses the covalent attachment of GGPP to the cysteine of a carboxyl-terminal CC or CXC motif of RAB proteins (PMID 11136552, 10737774, 35961942).

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