Anticorps Monoclonal anti-RAC2

• Phare
• Validé par KD/KO

RAC2 Monoclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

4C2H6

N° de cat : 60077-1-PBS

Synonymes

4C2H6, Gx, HSPC022, p21 Rac2, p21-Rac2

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Galerie de données de validation

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  WB analysis using 60077-1-Ig (same clone as 60077-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60077-1-Ig (RAC2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60077-1-PBS cible RAC2 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: RAC2 Protéine recombinante Ag1202
• Nom complet: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
• Masse moléculaire calculée: 21 kDa
• Poids moléculaire observé: 21 kDa
• Numéro d’acquisition GenBank: BC001485
• Symbole du gène: RAC2
• Identification du gène (NCBI): 5880
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.

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