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Anticorps Polyclonal de lapin anti-RAD23A

RAD23A Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11364-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of mouse testis tissue using RAD23A Polyclonal antibody (11364-1-AP)

    WB analysis of mouse testis using 11364-1-AP (same clone as 11364-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 11364-1-AP (RAD23A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11364-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse testis tissue using RAD23A Polyclonal antibody (11364-1-AP)

    WB analysis of mouse testis using 11364-1-AP (same clone as 11364-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 11364-1-AP (RAD23A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11364-1-PBS in a different storage buffer formulation.

Informations sur le produit

11364-1-PBS cible RAD23A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène RAD23A Protéine recombinante Ag1907
Nom complet RAD23 homolog A (S. cerevisiae)
Masse moléculaire calculée 40 kDa
Poids moléculaire observé 55 kDa
Numéro d’acquisition GenBankBC014026
Symbole du gène RAD23A
Identification du gène (NCBI) 5886
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RAD23A, also named as HHR23A, belongs to the RAD23 family. It is a multiubiquitin chain receptor involved in modulation of proteasomal degradation. RAD23A binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. It is proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. It is involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. It is also involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages and is required for the association of HIV-1 vpr with the host proteasome. This antibody is a rabbit polyclonal antibody raised against full length RAD23A of human origin.

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