Anticorps Polyclonal de lapin anti-RANK/TNFRSF11A

RANK/TNFRSF11A Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55293-1-PBS

Synonymes

TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK

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Galerie de données de validation

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  WB analysis using 55293-1-AP (same clone as 55293-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55293-1-AP (RANK antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55293-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55293-1-PBS cible RANK/TNFRSF11A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Masse moléculaire calculée: 66 kDa
• Poids moléculaire observé: 80-90 kDa
• Numéro d’acquisition GenBank: NM_003839
• Symbole du gène: TNFRSF11A
• Identification du gène (NCBI): 8792
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).

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