Anticorps Recombinant de lapin anti-RARG

RARG Recombinant Antibody for WB, Sandwich ELISA, Indirect ELISA, Sample test

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Sandwich ELISA, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

250399C1

N° de cat : 86098-1-PBS

Synonymes

NR1B3, RAR gamma, RARC, RAR-gamma, Retinoic acid receptor gamma

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Galerie de données de validation

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  WB analysis using 86098-1-RR (same clone as 86098-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86098-1-RR (RARG antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86098-1-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP02317-1

  Sandwich ELISA standard curve of MP02317-1, Human RARG Recombinant Matched Antibody Pair - PBS only. 86098-2-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag1991. 86098-1-PBS was HRP conjugated as the detection antibody. Range: 46.9-3000 pg/mL.

• 

  Sample test of MP02317-1

  The mean RARG concentration was determined to be 3.4 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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Informations sur le produit

86098-1-PBS cible RARG dans les applications de WB, Sandwich ELISA, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RARG Protéine recombinante Ag1991
• Nom complet: retinoic acid receptor, gamma
• Masse moléculaire calculée: 454 aa, 50 kDa
• Poids moléculaire observé: 50-60kDa
• Numéro d’acquisition GenBank: BC019098
• Symbole du gène: RARG
• Identification du gène (NCBI): 5916
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Retinoic acid receptors (RARs) are nuclear hormone receptors that act as ligand-dependent transcriptional regulators. In their liganded state, RARs activate transcription, whereas in their nonliganded form, they repress transcription of their target genes. RARs have numerous target genes, which have retinoic response elements in their promoter regions (PMID:17574023). RARG is a member of the retinoid acid receptor (RAR) family, along with RARA, which is known to be involved PML/RARA fusion of acute promyelocytic leukemia, and RARB. and rearrangement that conferred to leukemic cells acute promyelocytic leukemia-like morphologic and immunophenotypic features (PMID:20935257).

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