Anticorps Polyclonal de lapin anti-RAVER2
RAVER2 Polyclonal Antibody for IP, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
IP, ELISA
Conjugaison
Non conjugué
N° de cat : 32025-1-AP
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IP | cellules HEK-293T, |
Dilution recommandée
| Application | Dilution |
|---|---|
| Immunoprécipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
32025-1-AP cible RAVER2 dans les applications de IP, ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | RAVER2 Protéine recombinante Ag36879 |
| Nom complet | ribonucleoprotein, PTB-binding 2 |
| Masse moléculaire calculée | 74/72 kDa |
| Poids moléculaire observé | 75 kDa |
| Numéro d’acquisition GenBank | BC065303 |
| Symbole du gène | RAVER2 |
| Identification du gène (NCBI) | 55225 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).
Protocole
| Product Specific Protocols | |
|---|---|
| IP protocol for RAVER2 antibody 32025-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
