Anticorps Polyclonal de lapin anti-RAVER2

RAVER2 Polyclonal Antibody for IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IP, ELISA

Conjugaison

Non conjugué

N° de cat : 32025-1-AP

Synonymes

KIAA1579, Protein raver-2, Ribonucleoprotein PTB-binding 2



Applications testées

Résultats positifs en IPcellules HEK-293T,

Dilution recommandée

ApplicationDilution
Immunoprécipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

32025-1-AP cible RAVER2 dans les applications de IP, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène RAVER2 Protéine recombinante Ag36879
Nom complet ribonucleoprotein, PTB-binding 2
Masse moléculaire calculée74/72 kDa
Poids moléculaire observé75 kDa
Numéro d’acquisition GenBankBC065303
Symbole du gène RAVER2
Identification du gène (NCBI) 55225
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).

Protocole

Product Specific Protocols
IP protocol for RAVER2 antibody 32025-1-APDownload protocol
Standard Protocols
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