Anticorps Polyclonal de lapin anti-RAVER2
RAVER2 Polyclonal Antibody for IP, Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
IP, Indirect ELISA
Conjugaison
Non conjugué
N° de cat : 32025-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
32025-1-PBS cible RAVER2 dans les applications de IP, Indirect ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | RAVER2 Protéine recombinante Ag36879 |
| Nom complet | ribonucleoprotein, PTB-binding 2 |
| Masse moléculaire calculée | 74/72 kDa |
| Poids moléculaire observé | 75 kDa |
| Numéro d’acquisition GenBank | BC065303 |
| Symbole du gène | RAVER2 |
| Identification du gène (NCBI) | 55225 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).
