Anticorps Polyclonal de lapin anti-RBM20

RBM20 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31177-1-PBS

Synonymes

RNA binding motif protein 20, RNA binding protein

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Galerie de données de validation

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  IHC staining of rat heart using 31177-1-AP (same clone as 31177-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat heart tissue slide using 31177-1-AP (RBM20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31177-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 31177-1-AP (same clone as 31177-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 31177-1-AP (RBM20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31177-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31177-1-PBS cible RBM20 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RBM20 Protéine recombinante Ag34322
• Nom complet: RNA binding motif protein 20
• Masse moléculaire calculée: 134 kDa
• Numéro d’acquisition GenBank: NM_001134363
• Symbole du gène: RBM20
• Identification du gène (NCBI): 282996
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RBM20 (RNA binding motif protein 20) is a striated muscle-specific splicing factor that regulates alternative splicing of many cardiac genes encoding sarcomere and calcium-regulatory proteins (PMID: 36417486). RBM20 has been identified as a crucial RNA-binding protein that controls the splicing of TTN (PMID: 30547036). RBM20 is expressed in all striated muscles but is highest in cardiac tissue (PMID: 34575212).

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