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Anticorps Recombinant de lapin anti-REPS2

REPS2 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241136D3

N° de cat : 84016-4-PBS

Synonymes

REPS 2, RalBP1-interacting protein 2, RalBP1-associated Eps domain-containing protein 2, RalBP1 interacting protein 2, 241136D3

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of LNCaP cells using REPS2 Recombinant antibody (84016-4-RR)

    IF Staining of LNCaP using 84016-4-RR (same clone as 84016-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed LNCaP cells using REPS2 antibody (84016-4-RR, Clone: 241136D3 ) at dilution of 1:100 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84016-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84016-4-RR

    Affinity and Kinetic Characterization of 84016-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84016-4-RR against Human REPS2 were performed. The affinity constant is below 1 pM.

Informations sur le produit

84016-4-PBS cible REPS2 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène REPS2 Protéine recombinante Ag33764
Nom complet RALBP1 associated Eps domain containing 2
Masse moléculaire calculée72KD
Numéro d’acquisition GenBankNM_004726
Symbole du gène REPS2
Identification du gène (NCBI) 9185
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

REPS2 is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. There are 4 isoforms of the protein with two short (58 kDa) isoforms comprising 521 or 522 amino acid residues and two long (78 kDa) ones of 659 or 660 residues.

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