Anticorps Recombinant de lapin anti-RGNEF

RGNEF Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241975E4

N° de cat : 84570-2-PBS

Synonymes

ARHGEF28, p190-RhoGEF, p190RhoGEF, p190 RhoGEF, ARG28

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Galerie de données de validation

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  WB analysis using 84570-2-RR (same clone as 84570-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84570-2-RR (RGNEF antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84570-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01414-1

  Cytometric bead array standard curve of MP01414-1, RGNEF Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84570-2-PBS. Detection antibody: 84570-1-PBS. Standard: Ag10915. Range: 0.469-60 ng/mL.

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  Affinity and Kinetic Characterization of 84570-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84570-2-RR against Human RGNEF were performed. The affinity constant is below 1 pM.

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Informations sur le produit

84570-2-PBS cible RGNEF dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RGNEF Protéine recombinante Ag10915
• Nom complet: Rho-guanine nucleotide exchange factor
• Masse moléculaire calculée: 192 kDa
• Poids moléculaire observé: 192 kDa
• Numéro d’acquisition GenBank: BC012946
• Symbole du gène: RGNEF
• Identification du gène (NCBI): 64283
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGEF28, also known as RGNEF or p190RhoGEF, is a 190 kDa RNA binding protein (RBP) that contains a Dbl/PH domain capable of RhoA activation. ARHGEF28 interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates.

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