Anticorps Polyclonal de lapin anti-RGS9

RGS9 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17970-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 17970-1-AP (same clone as 17970-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 17970-1-AP (RGS9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17970-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 17970-1-AP (same clone as 17970-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 17970-1-AP (RGS9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17970-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17970-1-PBS cible RGS9 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RGS9 Protéine recombinante Ag11976
• Nom complet: regulator of G-protein signaling 9
• Masse moléculaire calculée: 622 aa, 71 kDa
• Poids moléculaire observé: 58 kDa, 70-75 kDa
• Numéro d’acquisition GenBank: BC022504
• Symbole du gène: RGS9
• Identification du gène (NCBI): 8787
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).

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