Anticorps Polyclonal de lapin anti-RHBDL3

RHBDL3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21671-1-PBS

Synonymes

EC:3.4.21.105, RHBDL4, Rhomboid related protein 3, Rhomboid-related protein 3, VRHO

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Galerie de données de validation

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  WB analysis using 21671-1-AP (same clone as 21671-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21671-1-AP (RHBDL3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21671-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21671-1-PBS cible RHBDL3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RHBDL3 Protéine recombinante Ag16499
• Nom complet: rhomboid, veinlet-like 3 (Drosophila)
• Masse moléculaire calculée: 404 aa, 45 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC100975
• Symbole du gène: RHBDL3
• Identification du gène (NCBI): 162494
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RHBDL3 (Rhomboid-related protein 3) is involved in a process known as regulated intramembrane proteolysis (RIP), where proteins are cleaved within the membrane to release functional polypeptides from their membrane anchors. It is expressed in several structures, including the central nervous system, embryo ectoderm, reproductive system, sensory organ, and thymus. RHBDL3 is also a prognostic marker in Glioblastoma multiforme, indicating its potential role in cancer-related pathways. It is expressed in various cell lines, particularly in those related to neuronal function and visual perception, with low cancer specificity.

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