Anticorps Polyclonal de lapin anti-RIN2

RIN2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31223-1-PBS

Synonymes

Ras and Rab interactor 2, Ras inhibitor JC265, RASSF4

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Galerie de données de validation

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  WB analysis using 31223-1-AP (same clone as 31223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31223-1-AP (RIN2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31223-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31223-1-PBS cible RIN2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RIN2 Protéine recombinante Ag35011
• Nom complet: Ras and Rab interactor 2
• Masse moléculaire calculée: 100 kDa
• Poids moléculaire observé: 100-120 kDa
• Numéro d’acquisition GenBank: NM_018993
• Symbole du gène: RIN2
• Identification du gène (NCBI): 54453
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RIN2 (Ras and Rab interactor 2), also known as RASSF4. RIN2 is mainly located in Golgi apparatus and participates in the process of material transport and secretion in cells. It is also distributed in cytoplasmic matrix, which may be related to signal transduction in cells. It is highly expressed in the brain, and also in the cerebellum, spinal cord and other nervous system tissues. RIN2 belongs to the family of Ras and Rab exchange factors and has a unique VPS9 domain. It can be used as a nucleotide exchange factor to activate the downstream small GTP enzymes Rab5 and R-Ras, thus starting intracellular signal transduction and regulating cytoskeleton recombination, synapse secretion and cell adhesion. The molecular weight of RIN2 is 100 kDa.

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