Anticorps Recombinant de lapin anti-RINT1

RINT1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241592C4

N° de cat : 84290-6-PBS

Synonymes

RINT 1, RAD50-interacting protein 1, HsRINT-1, HsRINT1, HsRINT 1

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Galerie de données de validation

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  WB analysis of rat brain using 84290-6-RR (same clone as 84290-6-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 84290-6-RR (RINT1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84290-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84290-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84290-6-RR against Human RINT1 were performed. The affinity constant is 0.551 nM.

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Informations sur le produit

84290-6-PBS cible RINT1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RINT1 Protéine recombinante Ag6145
• Nom complet: RAD50 interactor 1
• Masse moléculaire calculée: 91 kDa
• Poids moléculaire observé: 87 kDa
• Numéro d’acquisition GenBank: BC068483
• Symbole du gène: RINT1
• Identification du gène (NCBI): 60561
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RINT-1 was first identified as a Rad50-interacting protein that participates in radiation-induced G2/M checkpoint control. It also involved in regulation of membrane traffic between the endoplasmic reticulum and the Golgi. It interacts with p130, an Rb family protein, and together they regulate the telomerase-independent telomere length. Otherwise, it interacts with Zeste white 10 with its N-terminal region throughout the cell cycle.

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