Anticorps Recombinant de lapin anti-RIPK2

RIPK2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250069D9

N° de cat : 85760-4-PBS

Synonymes

CARD3, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARDIAK, CCK

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Galerie de données de validation

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  WB analysis using 85760-4-RR (same clone as 85760-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85760-4-RR (RIPK2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85760-4-PBS in a different storage buffer formulation.

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Informations sur le produit

85760-4-PBS cible RIPK2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RIPK2 Protéine recombinante Ag0909
• Nom complet: receptor-interacting serine-threonine kinase 2
• Masse moléculaire calculée: 61 kDa
• Poids moléculaire observé: 46-55 kDa, 61-72 kDa
• Numéro d’acquisition GenBank: BC004553
• Symbole du gène: RIPK2
• Identification du gène (NCBI): 8767
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RIPK2 is also named as CARDIAK, RICK, RIP2 and belongs to the receptor-interacting serine/threonine-protein kinase(RIPK) family. RIPK2 functions as a key signaling protein in host defense responses induced by activation of the cytosolic pattern recognition receptors (PRR) NOD1 and NOD2. It has also been reported to mediate other cellular responses, including TLR signaling, caspase 1 activation , apoptosis and autophagy(PMID:22685397). It has 2 isoforms produced by alternative splicing.

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