Anticorps Polyclonal de lapin anti-RNASEL

RNASEL Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22577-1-PBS

Synonymes

RNase L, RNS4, RNS 4, EC:3.1.26.-, 2-5A-dependent RNase

---

Galerie de données de validation

• 

  WB analysis using 22577-1-AP (same clone as 22577-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 22577-1-AP (RNASEL antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  WB analysis of RAW 264.7 using 22577-1-AP (same clone as 22577-1-PBS)

  RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 22577-1-AP (RNASEL Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 22577-1-AP (same clone as 22577-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 22577-1-AP (RNASEL Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 22577-1-AP (same clone as 22577-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22577-1-AP (RNASEL Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 22577-1-AP (same clone as 22577-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 22577-1-AP (RNASEL Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 22577-1-AP (same clone as 22577-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22577-1-AP (RNASEL Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 22577-1-AP (same clone as 22577-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using RNASEL antibody (22577-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 22577-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

22577-1-PBS cible RNASEL dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RNASEL Protéine recombinante Ag17409
• Nom complet: ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
• Masse moléculaire calculée: 741 aa, 84 kDa
• Poids moléculaire observé: 84 kDa; 73 kDa
• Numéro d’acquisition GenBank: BC115697
• Symbole du gène: RNASEL
• Identification du gène (NCBI): 6041
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RNASEL, also named as RNS4, is an endoribonuclease that functions in the interferon (IFN) antiviral response. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. There're some isoforms with calculated MW 84 kDa and 73 kDa.

{{ptg:RelatedPrimaryAntibodies}}