Anticorps Monoclonal anti-RND3

• Phare
• Validé par KD/KO

RND3 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, porc

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3H8F9

N° de cat : 66228-1-PBS

Synonymes

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3

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Galerie de données de validation

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  WB analysis of fetal human brain using 66228-1-Ig (same clone as 66228-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66228-1-Ig (RND3 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66228-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66228-1-PBS cible RND3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: RND3 Protéine recombinante Ag18839
• Nom complet: Rho family GTPase 3
• Masse moléculaire calculée: 244 aa, 27 kDa
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: BC012513
• Symbole du gène: RND3
• Identification du gène (NCBI): 390
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.

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