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Anticorps Polyclonal de lapin anti-RNF123

RNF123 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25260-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using RNF123 Polyclonal antibody (25260-1-AP)

    WB analysis using 25260-1-AP (same clone as 25260-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25260-1-AP (RNF123 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25260-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HeLa cells using RNF123 Polyclonal antibody (25260-1-AP)

    IP experiment of HeLa using 25260-1-AP (same clone as 25260-1-PBS)

    IP result of anti-RNF123 (IP:25260-1-AP, 4ug; Detection:25260-1-AP 1:600) with HeLa cells lysate 1200 ug. This data was developed using the same antibody clone with 25260-1-PBS in a different storage buffer formulation.

Informations sur le produit

25260-1-PBS cible RNF123 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène RNF123 Protéine recombinante Ag19653
Nom complet ring finger protein 123
Masse moléculaire calculée 1314 aa, 149 kDa
Poids moléculaire observé149 kDa
Numéro d’acquisition GenBankBC130632
Symbole du gène RNF123
Identification du gène (NCBI) 63891
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RING finger protein 123 (RNF123), also known as KPC1, is an E3 ubiquitin ligase that belongs to the RING-finger family of ligases that contain a 40-60-amino acid long RING domain which is essential for causing substrate ubiquitination (PMID: 29676528). RNF123 promoted TLR3/IRF7-induced type I IFN signaling and inhibited viral replication by degrading SOCS1 (PMID: 37014223).

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