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Anticorps Recombinant de lapin anti-RNF135

RNF135 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241606D8

N° de cat : 84984-1-PBS

Synonymes

RIG I E3 ubiquitin ligase, REUL, L13, EC:2.3.2.27, E3 ubiquitin-protein ligase RNF135

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of PC-12 cells using RNF135 Recombinant antibody (84984-1-RR)

    IF Staining of PC-12 using 84984-1-RR (same clone as 84984-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PC-12 cells using RNF135 antibody (84984-1-RR, Clone: 241606D8 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84984-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84984-1-RR

    Affinity and Kinetic Characterization of 84984-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84984-1-RR against Human RNF135 were performed. The affinity constant is 49.1 nM.

Informations sur le produit

84984-1-PBS cible RNF135 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

Réactivité Humain, rat
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène RNF135 Protéine recombinante Ag18821
Nom complet ring finger protein 135
Masse moléculaire calculée 432 aa, 48 kDa
Poids moléculaire observé 48 kDa
Numéro d’acquisition GenBankBC005084
Symbole du gène RNF135
Identification du gène (NCBI) 84282
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ring finger protein 135 (RNF135), located on chromosome 17q11.2, is a RING finger domain-containing E3 ubiquitin ligase that was identified as a bio-marker and therapy target of glioblastoma (PMID: 26856755). RNF135 facilitates RIG-I C-terminal ubiquitination to up-regulate RIG-I-mediated IFN signaling and suppress viral replication.

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