Anticorps Recombinant de lapin anti-RPL11

RPL11 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242147D7

N° de cat : 84670-3-PBS

Synonymes

242147D7, 60S ribosomal protein L11, CLL associated antigen KW 12, CLL-associated antigen KW-12, DBA7

---

Galerie de données de validation

• 

  WB analysis using 84670-3-RR (same clone as 84670-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84670-3-RR (RPL11 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84670-3-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse pancreas using 84670-3-RR (same clone as 84670-3-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 84670-3-RR (RPL11 antibody) at dilution of 1:5000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84670-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84670-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84670-3-RR against Human RPL11 were performed. The affinity constant is below 1 pM.

---

Informations sur le produit

84670-3-PBS cible RPL11 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: RPL11 Protéine recombinante Ag9356
• Nom complet: ribosomal protein L11
• Masse moléculaire calculée: 177 aa, 20 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC018970
• Symbole du gène: RPL11
• Identification du gène (NCBI): 6135
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibit 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.

{{ptg:RelatedPrimaryAntibodies}}