Anticorps Polyclonal de lapin anti-RRAD

• Phare
• Validé par KD/KO

RRAD Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27763-1-PBS

Synonymes

Ras associated with diabetes, RAD1, RAD, GTP-binding protein RAD, GTP binding protein RAD

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Galerie de données de validation

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  WB analysis using 27763-1-AP (same clone as 27763-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27763-1-AP (RRAD antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27763-1-PBS in a different storage buffer formulation.

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  WB analysis of SKOV-3 using 27763-1-AP (same clone as 27763-1-PBS)

  WB result of RRAD antibody (27763-1-AP; 1:5000; incubated at room temperature for 1.5 hours) with sh-Control and sh-RRAD transfected SKOV-3 cells. This data was developed using the same antibody clone with 27763-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27763-1-PBS cible RRAD dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RRAD Protéine recombinante Ag26869
• Nom complet: Ras-related associated with diabetes
• Masse moléculaire calculée: 33 kDa
• Poids moléculaire observé: 29-34 kDa
• Numéro d’acquisition GenBank: BC057815
• Symbole du gène: RRAD
• Identification du gène (NCBI): 6236
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RRAD is also named as RAD1. RRAD, a member of the Ras-like small GTPase family, was initially identified as a gene associated with Type II diabetes since it was found to be overexpressed in some Type II diabetic patients (PMID: 8248782). RRAD overexpression reduced insulin-stimulated glucose uptake in cultured muscle and adipocytes cells (PMID: 8798502). RRAD was found to be frequently down-regulated in different types of human cancers, including lung cancer, breast cancer, and nasopharyngeal carcinoma, etc, due to the hypermethylation of its promoter (PMID: 17195088).

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