Anticorps Monoclonal anti-RS1

RS1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A2D4

N° de cat : 68654-1-PBS

Synonymes

Retinoschisin, retinoschisin 1, RS, RS1, XLRS1

---

Galerie de données de validation

• 

  WB analysis using 68654-1-Ig (same clone as 68654-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68654-1-Ig (RS1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68654-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse retina using 68654-1-Ig (same clone as 68654-1-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 68654-1-Ig (RS1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68654-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

68654-1-PBS cible RS1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, rat, souris

• Réactivité: Humain, Lapin, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: RS1 Protéine recombinante Ag18885
• Nom complet: retinoschisin 1
• Masse moléculaire calculée: 26 kDa
• Poids moléculaire observé: 26 kDa
• Numéro d’acquisition GenBank: BC141638
• Symbole du gène: RS1
• Identification du gène (NCBI): 6247
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RS1 is also named as XLRS1. RS1 can bind negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. RS1 is required for normal structure and function of the retina (PMID:19093009). It may play a role in cell-cell adhesion processes in the retina (PMID:27114531). RS1 is high expression in the retina (at protein level) (PMID:10915776, PMID:9326935). It is detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer. At the macula, it is expressed in both the outer and inner nuclear layers and in the inner plexiform layer (PMID:10915776, PMID:10915776). And RS1 is undetectable in the inner plexiform layers and the inner nuclear layer (PMID:10915776)

{{ptg:RelatedPrimaryAntibodies}}