Anticorps Polyclonal de lapin anti-RSPH1

RSPH1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32033-1-PBS

Synonymes

Radial Spoke Head Component 1, Radial spoke head 1 homolog, Meichroacidin, Male meiotic metaphase chromosome-associated acidic protein, CT79

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Galerie de données de validation

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  WB analysis using 32033-1-AP (same clone as 32033-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32033-1-AP (RSPH1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32033-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32033-1-PBS cible RSPH1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RSPH1 Protéine recombinante Ag36560
• Nom complet: radial spoke head 1 homolog (Chlamydomonas)
• Masse moléculaire calculée: 309 aa, 35 kDa
• Poids moléculaire observé: 41 kDa
• Numéro d’acquisition GenBank: BC101519
• Symbole du gène: RSPH1
• Identification du gène (NCBI): 89765
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RSPH1 (Radial Spoke Head Component 1) encodes a male mid-meiotic chromosome-associated acidic protein involved in the structure and function of cilia and flagella. Pathogenic variants of RSPH1 lead to impaired spermatocyte motility and aberrant flagellar composition, which further contribute to male infertility. In addition to this, mutations in the RSPH1 gene lead to primary ciliary dyskinesia-24 (PCD-24), an autosomal recessive disorder that affects the motor function of cilia and flagella.

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