Anticorps Polyclonal de lapin anti-RSPO2

• Phare
• Validé par KD/KO

RSPO2 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

8

Avis (1)

N° de cat : 17781-1-AP

Synonymes

CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2

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Galerie de données de validation

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 2 publications below
• WB: See 7 publications below
• IHC: See 2 publications below
• IF: See 3 publications below

Informations sur le produit

17781-1-AP cible RSPO2 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, porc, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RSPO2 Protéine recombinante Ag11216
• Nom complet: R-spondin 2 homolog (Xenopus laevis)
• Masse moléculaire calculée: 243 aa, 28 kDa
• Poids moléculaire observé: 33 kDa
• Numéro d’acquisition GenBank: BC027938
• Symbole du gène: RSPO2
• Identification du gène (NCBI): 340419
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.

Publications

Species	Application	Title
human,mouse	WB,IF	Cardiovasc Res; Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis.; Authors - Bhupesh Singla
mouse	WB,IF	Int J Mol Sci; R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice.; Authors - Ahmed A Raslan
human	WB,IHC	J Cancer; miR-497-5p-RSPO2 axis inhibits cell growth and metastasis in glioblastoma.; Authors - Kun Chen
human	WB	DNA Cell Biol; Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.; Authors - Lei Gao
human	WB	Mol Biol Rep; RSPO fusion transcripts in colorectal cancer in Japanese population.; Authors - Kazuya Shinmura
mouse	IF	BMC Res Notes; R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.; Authors - S R Jackson ; KO Validated

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Marc (Verified Customer) (02-14-2023)

Used this antibody for immunofluorescence, but since the expression of this protein in spinal cord is low we used it together with a tyramide amplification kit. In this way, it works very good.

• Applications: Immunofluorescence
• Primary Antibody Dilution: 1:500
• Cell Tissue Type: Spinal Cord